High Quality Chemical API CAS 9041-93-4 Bleomycin Sulfate Bleomycin Shijiazhuang

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Bleomycin sulfate is one kind of white powder. It is soluble in water, methanol, slightly soluble in ethanol, practically insoluble in acetone, ethyl acetate, butyl acetate, ethyl ether.
Bleomycin sulfate is the sulfate salt of a complex natural product antibiotic. This compound approximates metals such as Fe(II) which then coordinate dioxygen to generate the active species. This Bleomycin-metal-dioxygen species is capable of inducing oxidative cleavage of the DNA backbone, leading to apoptosis. The species also degrades RNA, and has been reported to display selectivity for RNA over DNA.
Function of Bleomycin sulfate
Bleomycin is a broad-spectrum antitumor drug. Bleomycin is effective for squamous cell carcinomas, including cancers of
the head and neck, skin, esophagus, lungs, cervix, penis, thyroid, and malignant lymphomas. Bleomycin also has a certain
effect on brain tumors, malignant melanoma, and fibrosarcoma.
Application of Bleomycin sulfate
Bleomycin sulfate is the sulfate salt of a complex natural product antibiotic. This compound approximates metals such as
Fe(II) which then coordinate dioxygen to generate the active species. This Bleomycin-metal-dioxygen species is capable
of inducing oxidative cleavage of the DNA backbone, leading to apoptosis. The species also degrades RNA, and has
been reported to display selectivity for RNA over DNA.

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