High Quality 99%Min Doxorubicin Hydrochloride Powder Shijiazhuang

  CD / DVD   (Item ID: 159000)

Product name Doxorubicin hydrochloride
CAS Number 25316-40-9
Synonyms ADRIACIN;ADRIBLASTINA;ADRIBLASTINAHYDROCHLORIDE;ADRIAMYCINHCL;ADRIAMYCINHYDROCHLORIDE;(8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7Chemicalbook,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dionehydrochloride;14-HYDROXYDAUNOMYCINHCL;14-HYDROXYDAUNOMYCINHYDROCHLORIDE
Molecular formula C27H30ClNO11
Molecular weight 579.98
Purity 99%
Appearance White powder
EINECS number 246-818-3


More gentle than star chemical called 10 - [(,3,6 amino - 3-2-3 to oxygen - alpha - L - suzhou pyran base) - oxygen] - 6-7,8,9,10 - four hydrogen,8,11-3 hydroxy - 8 - (hydroxyl acetyl) - 1 - methoxy - 5, 12 - nai diketone hydrochloride, alias doxorubicin hydrochloride Is tasted more gentle than star for orange freeze-dried powder, soluble in water, the melting point of 216 more gentle than the star is also called the adriamycin (ADM), commonly used in clinical chemotherapy of human cancer More gentle than the star is a kind of chemical semi-synthetic anthracene ring drug class antitumor antibiotics with soft erythromycin and other anthracene ring toxin, more gentle than the star can insert and cellular DNA, DNA synthesis It is commonly used in the treatment of various cancers, such as hematological malignancies, solid tumors and soft tissue sarcomas
Applications:
1.Adriamycin is an anti-tumor antibiotic, which can inhibit the synthesis of RNA and DNA, and has the strongest inhibition on RNA. It has a wide anti-tumor spectrum, and has an effect on a variety of tumors. It is a cycle non-specific drug, and has killing effect on tumor cells of various growth cycles
2.Antitumor antibiotic, doxorubicin effect on cardiac mitochondrial DNA inhibitors of reverse transcriptase and RNA polymerase, immunosuppressants; Insertable DNA strands are clinically used as cancer chemotherapeutic agents for acute and chronic leukemia and malignant lymphoma
3.Doxorubicin hydrochloride is an antibiotic anti-tumor drug, which can penetrate into cells and cross and bind with DNA of tumor cells, inhibit DNA replication, block the action of RNA polymerase and inhibit RNA synthesis. Its cytotoxic effect is related to the formation of free radicals, the combination of tumor cell membrane and the rupture of cell membrane. Widely used in cell culture or rat nephropathy, myocardial ischemia and other aspects of modeling materials; Used to inhibit macromolecular biosynthesis
4.For the treatment of acute lymphoblastic leukemia, acute granulocytic leukemia, Hodgkin's disease and non-Hodgkin's disease, lymphoma, breast cancer, lung cancer, and ovarian cancer

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