The Atopic Dermatitis Drug Fluocinolone Acetonide CAS: 67-73-2 Shijiazhuang

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Product Name Fluocinolone acetonide
CAS 67-73-2
Appearance White crystal powder
Molecular formula C24H30F2O6
Molecular Weight 452.54
Assay 98%
Shelf Life 24 months when properly stored
Storage Keep in a cool, dry, dark location
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocor tisone derivative. The fluo rine substitution at position 9 in the steroid nucleus greatly enhances its activity.

It was first synthesized in 1959 in the Research Department of Syntex Laboratories S.A. Mexico City.Preparations containing it were first marketed under the name Synalar. A typical dosage strength used in dermatology is 0.01-0.025%. One such cream is sold under the brand name Flucort-N and includes the antibiotic neomycin.

Function

The usual prescription concentration is 0.05% as a topical cream, ointment, solution, or gel. The application area should normally not be covered after application. In certain cases, the physician may recommend the use of anocclusive dressing after application to increase the rate and depth of absorption. The frequency of application depends on the condition being treated and the area affected, but most often it should be applied 2 to 4 times a day.

Fluocinonide ranks as a "high-potency" (second-highest rank) topical corticosteroid. Minimal amounts should be used for a minimal length of time to avoid the occurrence of adverse effects.[medical citation needed].

Beta me thasone is also used for low renin and low aldosterone syndrome and plant nerve lesions orthostatic hypotension caused by etc.

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